by jskm » October 17th, 2007, 5:02 pm
I'm definitely not offended; I have done loads of research myself. I lost a career in the military over this illness, I wasn't about to just dance along singing happy tunes, not knowing anything about it.
I know that seroquel is an AAP. That's why my pdoc would rather use it as a sleep aid first than a regular sleep aid, as I said, any side effects of mild mood boosting would be a bonus on top of it being a sleep aid. According to Astra Zenica, the manufacturer of seroquel, the therapeutic dose of seroquel for bipolar disorder for most patients is between 400-800mg per day, though a few may respond as low as 100mg day. 25mg per day is nowhere a therapeutic dose as an AAP, so it's unlikely that I'm getting this benefit from it. It definitely doesn't knock me out either, it just puts me in a relaxed state. The only thing that ever knocked me out was Zyprexa.
There are six anticonvulsants that are used as mood stabilizers; three are FDA approved to do so, the other three are trileptal--closely related to tegretol (one of the FDA approved ones) this was going to be my next choice after topa, my sister did well on this one; topamax (discussed below); and neurontin--this one actually doesn't do so well.
Depakote is one of the ACs that are FDA approved for treating bipolar disorder--it is the most commonly used mood stabilizing drug today along with lithium acc. to the NIMH. I had my levels checked monthly on this drug and I stayed at 86 the entire time I was on it.
Topamax is hit or miss. It works on the temporal lobe, so you will either love it or hate it. If your problems are in the temporal lobe, then you'll love it, if they're not, it won't do squat for you and you'll hate it. That's why you'll find such hot and cold reviews for it with no gray area. It's the same with pdocs prescribing it. Some won't touch it because of its spotty performance, some will. Luckily for me mine was one who's not afraid of trying it, because for me it's working very very well. I needed something to stop my weight gain and possibly help with weight loss, and this drug is well known for exactly that as well as potentially stabilizing mood. It was an excellent choice to try. (BTW I also have migraines, which is another reason my pdoc chose this med for me.)
There are a lot of AAPs out there, and Zyprexa was one that worked well for me as far as controlling my illness, but it was terrible for me physical healthwise. I just wasn't about to try another AAP with weight gain side effects. I had tried an AC (depakote) for mood stabilization and done well on it mood wise, so we felt safe trying another AC. If the topa stops working for me, I might consider one of the AAPs because the Z did work SO WELL for me mood wise, but it would have to be one WITHOUT weight side effects. So that rules out Zyprexa, Seroquel at the therapeutic dose for me, and Risperdal. There's Abilify, but I don't like this stuff--this one isn't serotonergic but instead messes with your dopamine activity and for some reason this just bothers me. This leaves possibly Geodon, but that also messes somewhat w/ dopamine, so I'm a little leery. I"m still reading about these last two; I find them confusing and I'm still trying to figure them out.
Last edited by
jskm on October 17th, 2007, 5:42 pm, edited 1 time in total.
Restart date 10/16/2007
Age: 27 Height: 5' 2"