24K is right-- hunger should go away after the first 3 days or so. Now, we can't lie to you-- the first 3 days can be very uncomfortable for some people! Some have headaches, some are ravenously hungry, some are lightheaded; others do just fine. But there are things you can do to prepare yourself-- make sure you drink lots of water, eat your medifoods every 3 hours or so, make sure you're getting enough sodium and potassium (by drinking 2 MF FastSoups or cups of bouillion per day), and take aspirin or other pain relievers to preempt any headaches.
After the first 3 days, it does get easier, and hopefully your migraines will stay away as the pounds melt from you...!
Anyway, welcome! Read as much as you can; this board has a lot of great info and it has certainly helped me through the good times and bad! Come here and read, lurk, post, whatever you like-- you'll learn a lot, help others, and distract yourself from any foody thoughts that threaten to derail your efforts. We'll get there togather!